The predicted orientation of the Cas9 protein on the AFM substrate is shown, and a simulated AFM image calculated in the scanning view perspective shows remarkable agreement with previous HS-AFM ...

A collaboration team of researchers from the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, the Institute of Transformative Bio-Molecules (WPI-ITbM), Graduate School of Science at ...

One of the key reasons for cancer mortality is caused by the highly invasive behavior of cancer cells, which is often due to aggressive metastasis. Metastasis is facilitated by various growth factors ...

(Nanowerk News) Allowing the direct observation of biomolecules in dynamic action, high-speed AFM has opened a new avenue to dynamic structural biology. An enormous amount of successful applications ...

In video microscopy techniques, a practical issue is how to properly assign moving features. Indeed, any video recording setup has a finite frame rate, and if several identical (or similar) moving ...

New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques. (Nanowerk News) An enzyme type noted in several ...

In this interview, News-Medical Life Science talks to Professor Toshio Ando about his interest in high-speed AFM and how it can revolutionize the observation of protein molecules. How did your ...

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and ...