When adult humans and animals severely injure their spinal cord, they become irreversibly paralyzed and are no longer able to move body parts controlled by the section of the spinal cord below their ...

The analysis of the human brain is a central goal of neuroscience. However, for methodological reasons, research has largely focused on model organisms, in particular the mouse. Now, neuroscientists ...

Parvalbumin (PV) interneurons act as the brain’s rhythm keepers. By regulating local circuit activity and maintaining excitation–inhibition balance, they help stabilize cortical network function. When ...

A study led by Dr. Marco Bocchio in the Durham University Department of Psychology reveals how specific brain cells called interneurons can act as our in-built traffic controllers. The findings are ...

To expand the understanding of memory, a research team has developed a technology called LCD-eGRASP (local circuit dual-eGRASP) that can label synapses of neural circuits within a specific brain ...

Memory, a fundamental tool for our survival, is closely linked with how we encode, recall, and respond to external stimuli. Over the past decade, extensive research has focused on memory-encoding ...

Xiaojing Tang et al. at Chongqing Institute for Brain and Intelligence recently published a study in Science Bulletin titled “Parvalbumin Interneurons Are Essential for Tonotopy Strength in the ...

Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epileptic seizures. The researchers say that targeting the ...

Labeling of intraregional synapses using LCD-eGRASP in the basolateral amygdala (BLA). Engram cells (Red), Non-engram cells (White), synapses from activated inhibitory interneurons (yellow), and ...