Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

Peptide nucleic acids (PNAs) represent a revolutionary class of synthetic nucleic acid analogues, in which the traditional sugar–phosphate backbone is replaced by a neutral N-(2-aminoethyl) glycine ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Alan Herbert, Founder and President of InsideOutBio, discusses the evolution of biological concepts related to DNA and protein structures ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Scientists developed a light-responsive artificial nucleic acid that enables reversible, controllable crosslinking within DNA, opening doors for nanomedicine, DNA nanotechnologies and drug delivery.

LL-37 continues to attract scientific interest due to its unique structural characteristics and its diverse interactions within biological systems. As the only known cathelicidin-derived peptide, LL-3 ...